Advanced treatment

RF Microneedling with PDRN

Designed to tighten, stimulate collagen, and improve your skin texture — delivered with precision and care.

What Is RF Microneedling?

More Than Microneedling


RF Microneedling combines the controlled micro-injuries of traditional needling with the added power of radiofrequency energy — delivered precisely beneath the skin’s surface using the Melia RF device.

This treatment creates controlled micro-channels while delivering heat into deeper tissue layers, triggering collagen and elastin production. PDRN (Salmon DNA): a regenerative ingredient derived from purified DNA fragments, is applied through those channels to accelerate healing, reduce inflammation, and improve how the skin rebuilds. The result is firmer, smoother skin with more consistent, longer-lasting outcomes.

"This isn't just a treatment. It's a more intelligent way for your skin to heal."

session length

45 – 60 min

Including preparation and aftercare guidance

DOWNTIME

Minimal

Mild redness for 24 to 72 hours

results visible

2 – 6 Weeks

With continued improvement over 3–6 months

Recommended sessions

3 – 6

Determined at your complementary consultation

see it in action

RF Microneedling Treatment


WHAT RF MICRONEEDLING

Can Address


RF Microneedling is highly adaptable. Your provider will review your concerns during your consultation and confirm whether this treatment is the right fit for your goals.

common concerns

What It Can Treat

Treatment areas

Where It Can Be Applied

for the best results

Treatment Instructions


Pre-treatment instructions
  • No makeup on the day of treatment.
  • Shave excess hair the night before (men should be clean-shaven).
  • Avoid sun exposure and self-tanners for 4 weeks prior.
  • Avoid waxing, depilatories, and irritating treatments for 1–2 weeks prior.
  • Notify the clinic of any changes to your health or medications.
  • If you’re prone to cold sores, antiviral medication may be needed.
  • Stop aspirin, ibuprofen, fish oils, vitamin A/E, and similar supplements 1 week prior.
  • Avoid caffeine and alcohol for a few days before.

First 24 Hours

  • Cleanse with lukewarm water only — no soap or cleanser.
  • Apply HA Quenching or the Alastin System 3× daily.
  • Limit mask use; if you wear one, make sure it’s clean.
  • Sleep on freshly laundered pillowcases.

24–72 Hours

  • Switch to a gentle cleanser.
  • Continue HA Quenching or Alastin 3× daily.
  • Apply SPF 30+ every morning.
  • Moisturizer and makeup are okay (waiting the full 72 hours is preferred).

After 72 Hours, Until Your Next Treatment

  • Continue with a gentle cleanser.
  • Apply HA Quenching or Alastin 2× daily, or stick with your gentle cleanser if you don’t have either.
  • Daily SPF is a must.
  • If you use Pigment Control Cream, restart nightly (minimum 2–3× per week).

General Aftercare

  • Expect redness, swelling, and possible bruising for several days to a few weeks.
  • Cool the area with a fan or A/C — no ice unless directed by your provider.
  • Keep the treated area clean for 2 days. Avoid hot tubs, saunas, and other heat sources.
  • Avoid irritating skincare (retinoids, acids, benzoyl peroxide) until fully healed.
  • If you use Pigment Control Cream, resume once healed (3–7 days post-treatment) and stop again 48–72 hours before your next session.
  • Treatments are typically repeated every 4–6 weeks.

common questions

Frequently Asked Questions


Is RF Microneedling safe?

Yes. RF Microneedling has an established safety profile across a wide range of skin types. At Pendeza, all treatments are performed by licensed professionals using the Melia RF device, which allows for precise, controlled delivery of both microneedles and radiofrequency energy. Your provider will review your full medical history before recommending treatment.

Topical numbing cream may be applied before your session, making the procedure comfortable for the vast majority of clients. Most describe it as mild warmth or pressure — not pain.

You may notice initial improvements in texture and tone within a few days. Collagen production continues over time, with ongoing improvement over several weeks and with a series of treatments.

That’s exactly what your consultation is for. Your provider will review your skin, your goals, and your timeline — and give you an honest recommendation.

Yes. This treatment is often part of a broader plan and may be combined with other therapies to enhance results. 

Upgrade in the same session: RF Microneedling with PDRN is already the enhanced version of standard RF Microneedling — the PDRN serum absorbs deeply through the micro-channels created during treatment, where it accelerates healing, reduces post-treatment redness, and boosts cellular repair. 

Build a treatment series: This treatment pairs well with a chemical peel or dermabrasion when spaced as part of a customized plan. Peels address surface texture and tone; dermabrasion smooths and resurfaces — both complement the deeper collagen work this treatment does. Your provider will recommend the right sequence and timing based on your skin goals.